Living human cells under controlled oxidative stress — AOX Profile biological measurement
AOX Profile™

The biological standard
for antioxidant efficacy.

AOXP turns antioxidant efficacy into a measured, certified and comparable biological standard, helping companies quantify how ingredients, formulations and finished products protect living cells against oxidative damage through a panel of 10+ cellular models, regardless of sector or application.

Living human cells under controlled oxidative stress — AOX Profile biological measurement
0K+Live-cell
measurements
0+Years of
proprietary R&D
0+Years of commercial
validation
0Peer-reviewed
publications

incl. Nature Scientific Reports →
0Active European
patents
0+Cell
models
0Antioxidant pathways
measured
Antioxidant claims without a comparable biological standard across the market
Why a biological standard

Why antioxidant efficacy needs a biological standard.

Antioxidant efficacy sits at the intersection of biological relevance and market confusion. AOXP connects both through live-cell measurement.

Oxidative stress is a shared biological mechanism

Oxidative stress contributes to cellular damage across skin, nutrition, functional health, longevity, recovery and cellular resilience. AOXP focuses on what can be measured directly in living cells: how ingredients and products protect cellular systems under controlled oxidative stress.

The market lacks comparable proof

Antioxidant claims are everywhere, but most products remain difficult to compare biologically. Ingredient suppliers, formulators, brands, prescribers and buyers need a shared reference to evaluate efficacy beyond marketing language.

The market is not missing another antioxidant claim. It is missing a trusted biological profile.

AOX Profile™

A biological identity,
not a single score.

The AOX Profile™ evaluates cellular protection across four independent pathways — in living human cells, under controlled conditions. It does not reduce biology to a single number. It creates a profile that brands can prove, prescribers can trust and consumers can compare.

01
Tested cell model
Specified human cell type. Results always model-referenced, never abstracted.
02
Overall performance class A–E
Overall class derived from the pathway profile. It summarizes the profile without replacing the underlying biological dimensions.
03
Four pathway scores /100
Independent biological dimensions. Strengths and weaknesses made visible.
04
Validity & communication rights
Certification and public display rights are separately licensed. Private by default.
Illustrative certified profile · Liver cells
AOX
Profile™
A
B
C
D
E
Overall class · pathway-derived
Very good · Overall 71/100
Liver cells (HepG2)
Radical neutralization88 / 100
NRF2 gene response36 / 100
Membrane protection41 / 100
H2O2 / CAT clearance52 / 100
Valid until 2027AOXP.AI / AOX-LV-0814

Pathway scores are fixed quantitative scores over 100, not percentiles or moving market rankings.

AOX Profile™ evaluates antioxidant efficacy in defined biological models. Not a clinical aging or lifespan claim.

Positioning

A new standard, for a new category, on proven models.

SPFUV protection
NutriScoreNutrition quality
EcoVadisESG performance
AOX Profile™Antioxidant efficacy
Confidential by design

Start privately. Communicate only when ready.

AOXP is designed for confidential industrial adoption. Companies can first measure, compare and optimize products privately. Certification and communication rights are separate steps, activated only when appropriate.

Private measurement
→
Optimization or certification
→
Optional communication rights

AOXP technology trusted across
leading scientific and industrial organizations

10 years of
commercial traction
1,030+ studies
delivered
LAAS / CNRSIPBSINSERMINRAEPharmadevANSESDGACooper / OenobiolSymriseNexiraInstitute of Nutrition and Functional FoodsPremium CosmeticsNutraceuticalsIngredient SuppliersFunctional Foods & BeveragesAcademic & Research Platforms10 years of
commercial traction
1,030+ studies
delivered
LAAS / CNRSIPBSINSERMINRAEPharmadevANSESDGACooper / OenobiolSymriseNexiraInstitute of Nutrition and Functional FoodsPremium CosmeticsNutraceuticalsIngredient SuppliersFunctional Foods & BeveragesAcademic & Research Platforms
Applications

Applications across the value chain.

AOX Profile™ is not a single test. It is a measurement layer that runs the length of the value chain — from raw ingredient to consumer choice.

Select a stage.

01Objectify the value of what you sell.Ingredient suppliers
How do you prove an active’s biological value and defend its price?
An AOX Profile™ on your ingredient turns a marketing claim into a measured, comparable biological argument — one your sales team can place directly in technical dossiers and brand conversations.
R&D screeningCertified ingredient profileB2B communication rights
Certified AOX Profile of an antioxidant ingredient for ingredient suppliers
02Choose raw materials on biology, not brochures.Manufacturers · Sourcing
Which actives actually perform inside living cells?
Predictive estimation and biological screening let you compare candidate ingredients on measured efficacy and anonymized benchmarks — before you commit a single formula.
Predictive estimationR&D screeningBenchmark data
Biological comparison of candidate antioxidant ingredients for sourcing decisions
03Formulate and optimize on measured efficacy.Manufacturers · Formulation
Does the formula protect cells — and how do I make it better?
Exploratory screening and optimization loops reveal which biological pathways your formula strengthens, and where it can be improved, before any public commitment.
PredictiveExploratory screeningOptimization loops
Antioxidant formulation optimization across cellular pathways
04Verify efficacy stays constant, lot after lot.Manufacturers · Quality control
Is biological efficacy consistent across production?
Recurring profiling tracks pathway performance over time, turning antioxidant efficacy into a measurable quality-control parameter along the production chain.
Recurring profilingConsistency monitoring
Batch-to-batch antioxidant efficacy quality control
05Prove efficacy to your customers.Manufacturers · Product claims
How do I substantiate an efficacy claim without regulatory or reputational risk?
A certified AOX Profile™ gives a defensible, third-party biological basis for your claims — public display licensed separately, private by default.
Certified profilingCommunication rights (opt-in)
Certified AOX Profile supporting a substantiated product efficacy claim
06Compare and choose on biology.Consumers & prescribers
Which product actually protects cells?
Certified public profiles let consumers and prescribers compare antioxidant efficacy across products on one common biological scale — the visible layer of the standard.
Certified public profilesComparability
Consumers and prescribers comparing certified antioxidant efficacy across products

Every profile is private by default. Public communication is a separate, opt-in licence — protecting the value of certified data and preserving the asymmetry between private intelligence and public profiles.

Markets & Themes

Where antioxidant efficacy creates value.

AOXP is not limited to one product category. It standardizes a shared biological question across markets: how well does a product, active or formulation protect living cells under controlled oxidative stress?

AOXP maps antioxidant efficacy across major biological and commercial territories where oxidative stress, cellular protection and redox balance shape product credibility.

Technology · LUCS

LUCS: live-cell antioxidant measurement under controlled oxidative stress.

The LUCS methodology measures how living cells respond to controlled oxidative stress across four antioxidant pathways.

LUCS — four antioxidant pathways measured in a living cell under controlled oxidative stress
1Radical neutralization
2Gene activation (NRF2 pathway)
3Membrane protection
4Hydrogen peroxide elimination (catalase-like)
The four cellular assays AOP1, AOP2, AOP3 and AOP CAT mapped onto a living cell

The 4 cellular assays AOP1, AOP2, AOP3 and AOP CAT ensure a complete study of the mechanism of action involved in the antioxidant effect.

Quercetin total cellular antioxidant efficacy score deduced from the combination of the four assays

The total cellular antioxidant efficacy score is deduced from the combination of the 4 assays.

Why this is different

Chemical assays measure antioxidant chemistry.
LUCS measures live-cell response under controlled oxidative stress.
AOX Profile™ turns these responses into standardized, comparable biological profiles.

LUCS Protocol
01
Controlled oxidative stress
02
Living-cell response
03
4 antioxidant pathways
04
Standardized AOX Profile™ output

SOD pathway in development — not yet part of the certified AOX Profile™ framework.

Live-cell biology transformed into digital intelligence
The Platform

Live-cell biology transformed into digital intelligence.

Three interconnected technology layers convert complex redox biology into standardized, comparable and AI-augmentable data — turning antioxidant efficacy into a quantifiable market standard for the first time.

Digital intelligence platform visualization
01
LUCS — Live Under Controlled Stress
Patented live-cell measurement protocol. Four antioxidant pathways measured simultaneously in living human cells under calibrated oxidative stress.
02
AOX Profile™ Standard
Biological outputs converted into standardized, certified and licensable profiles. Multi-dimensional. Comparable across products, ingredients and categories.
03
Data Intelligence & AI Layer
Expanding biological dataset enabling predictive formulation, category benchmarking, ingredient synergy mapping and personalized antioxidant intelligence.
Industrial Qualification Funnel

From broad candidate portfolios to certified biological value

AOXP helps ingredient suppliers, formulators and brands move from large unqualified portfolios to selected candidates with measurable, comparable and certifiable antioxidant profiles.

AOXP industrial qualification funnel — from a broad candidate universe to a certified AOX Profile
01Large candidate universeIngredients, extracts, molecules, blends and finished products

Most ingredient and product portfolios contain multiple antioxidant claims, but limited biological visibility. AOXP starts by mapping a wide universe of extracts, molecules, blends, formulations and finished products.

02Accessible predictive triage (coming soon)Low-friction screening to prioritize what deserves biological measurement

An initial low-friction screening layer helps prioritize which candidates deserve deeper biological investigation. It reduces exploration cost without replacing live-cell measurement or certification.

03Private biological profilingMeasured live-cell response across defined pathways and cell models

Selected candidates are measured confidentially in defined live-cell models. AOXP reveals how each candidate performs across oxidative stress pathways, without public exposure.

04Candidate selection & optimizationSelect, improve or discard

The strongest candidates move forward. Others can be reformulated, optimized or deprioritized before any certification or communication decision is made.

05Certified AOX Profile™Convert validated performance into a structured biological identity

Validated candidates can be converted into an AOX Profile™, a structured biological profile showing performance by cell model and pathway, with certification validity.

06Communication & value capturePublic visibility only when licensed

Only licensed profiles become public. Brands and suppliers can turn certified biological performance into communication rights, differentiation, technical dossiers, prescriber confidence and market visibility.

The funnel protects adoption. Industrial partners can explore privately, select intelligently, optimize where needed, and communicate only when the biological profile is strong enough to support market-facing value.

Beyond product qualification: linking cellular profiles to human biology

AOX Profile™ qualifies how ingredients and products perform in controlled biological models. Over time, AOXP can connect cellular profiles with human biomarker studies, including oxidative stress, inflammation and aging-related indicators, to support product-to-human biology translation, personalization and longitudinal data intelligence.

This extension is designed as a biological correlation layer, not as a clinical aging, disease prevention or lifespan claim.

Services

What AOXP does, concretely.

Four ways to put live-cell antioxidant measurement to work — from first profiling to market intelligence.

01
Available
Private Ingredient Profiling
Biological profiling of ingredients and actives across antioxidant pathways, benchmarked anonymously.
Contact us →
02
Available
Private Formulation Screening
Screening and optimization of formulas on measured cellular efficacy, before any public commitment.
Contact us →
03
Available
Certified AOX Profile™
Full AOX Profile™ across 4 pathways. Overall performance class. Validity period. Private by default — communication license as annual opt-in.
Contact us →
04
Available
Benchmark & Data Intelligence
Category benchmarking, competitive positioning and data intelligence from the AOXP dataset.
Contact us →
Engagement formats

How to start.

Four engagement tiers. Pricing on request; tiers describe scope, not a fixed catalog.

Entry
Discovery
First biological measurement. Understand your position privately before any decision.
  • LUCS measurement, 1–2 pathways
  • Private results, no communication rights
  • Anonymized benchmark position
  • Certification viability assessment
Most requested
Profile
Full certified AOX Profile™. Communication rights optional. One SKU.
  • Full LUCS measurement, 4 pathways
  • AOX Profile™ certified
  • Overall performance class A–E
  • Communication license (annual opt-in)
  • Annual recertification
Scale
Portfolio
Multiple SKUs. Category benchmarking. Optimization programs included.
  • 2–10 SKU certifications
  • Multi-category cell model coverage
  • Market benchmarking report
  • Formulation optimization loop
  • Priority scheduling
Enterprise
Enterprise
Custom deployment. Data intelligence. Multi-geography. Strategic partnership.
  • Unlimited SKU volume agreements
  • Data & benchmarking platform access
  • AI formulation intelligence (roadmap)
  • Geographic license management
  • Dedicated scientific liaison

Founding consortium members benefit from specific conditions. All pricing provided individually.

Founding Partner Program

Shape the standard.
Join the founding partners.

For selected ingredient suppliers, brands, formulators, clinics, retailers and scientific partners interested in shaping the first wave of AOX Profile™ adoption.

The cohort is limited. Applications are reviewed individually.

Ingredient suppliersBrandsFormulatorsClinicsRetailersScientific partners
Why join
01
Influence the standard
Direct input on methodology, cell model selection and category coverage as the AOX Profile™ framework develops.
02
Early data positioning
Access anonymized benchmark data before the market reference layer is publicly established.
03
Founding conditions
Preferential pricing and scheduling reserved exclusively for founding cohort members.
Contact

Get in touch.
We respond individually.

Whether you are exploring a first measurement, considering certification, interested in data intelligence, or simply want to understand what the AOX Profile™ could mean for your product or portfolio — we are available for a direct conversation.

All inquiries are handled with full confidentiality. No unsolicited follow-up.

Direct contact
hello@aoxp.ai
Send us a message
All messages treated with full confidentiality.

AOXP does not share your data with third parties.